When you plan to purchase liquid chromatography equipment for laboratory research or industrial testing, you may be troubled by a series of questions. What type of liquid chromatography is most suitable for your sample analysis needs, such as separating high-boiling organic compounds or trace biological molecules? How to ensure that the selected equipment meets the strict accuracy and sensitivity requirements of your industry? And do you clearly understand the differences in application scenarios between different models of liquid chromatography, so as to avoid mismatches between equipment functions and actual testing tasks?
Liquid chromatography is a core analytical technology widely used in fields such as biopharmaceuticals, food safety, and environmental monitoring. Mastering its specific types and characteristics is crucial for selecting the right equipment. The following will detail the types, brand product categories, advantages, material grades, and application fields of liquid chromatography to help you make informed decisions.
Common Types Of Liquid Chromatography
On the market, liquid chromatography is mainly divided into several types based on separation principles and application scenarios. High-Performance Liquid Chromatography (HPLC) is the most widely used type, with high separation efficiency and fast analysis speed, suitable for most organic compound detection. Ultra-High Performance Liquid Chromatography (UHPLC) has higher pressure resistance and better sensitivity, which can shorten the analysis time by more than 50% compared with HPLC and is often used in high-throughput testing scenarios. Two-Dimensional Liquid Chromatography (2D-LC) combines two different separation systems, expanding the range of detectable substances and is applicable to the screening of complex matrices such as serum exogenous exposure. In addition, there are specialized types such as Ion-Exchange Chromatography for ionic compound separation and Size-Exclusion Chromatography for macromolecular substance analysis.
Maxi Scientific’s Liquid Chromatography Categories
Maxi Scientific Instruments (Suzhou) Co., Ltd., focusing on the chromatography field, provides a complete range of liquid chromatography-related products. Its core products include Ghost-Sniper Columns with performance comparable to original products, PEEK HPLC accessories, and 316L stainless steel capillaries. These products have the advantages of affordable prices, short delivery times, and strong corrosion resistance. For example, the 316L stainless steel capillary adopts a special protective process, which not only has excellent sealing performance but also can be easily installed by hand, suitable for matching with various liquid chromatography systems.
The Advantage of Liquid Chromatography
In terms of general advantages, liquid chromatography can analyze 80% of organic compounds, especially high-boiling, thermally unstable, and biologically active substances that are difficult to handle by gas chromatography. Its detection sensitivity is high, and the ultraviolet detector can reach 0.01ng, which can meet the trace analysis needs.
For common types, HPLC has the advantages of reusable columns and small sample consumption; UHPLC has better separation efficiency (three times that of conventional HPLC) and lower cross-contamination rate; 2D-LC can expand the oil-water partition coefficient range of detectable substances to -8 to 12, realizing high-coverage screening of multiple pollutants.
Maxi Scientific’s products have unique advantages. Its Ghost-Sniper Column adopts a unique production process, which ensures stable performance while reducing costs. The capillary products have a long service life, which can reduce the frequency of equipment replacement for users and save operating costs.
Liquid Chromatography Material Grades
Liquid chromatography’s core components have strict material standards. Taking the column as an example, the stationary phase uses porous particles with a particle size of 5-10μm for HPLC and smaller particles for UHPLC to improve separation efficiency. The pipeline is mostly made of 316L stainless steel (corrosion-resistant) or PEEK material (suitable for strong acid and alkali samples).
In terms of industry grade standards, the equipment needs to meet the performance indicators such as flow rate accuracy (±1% or ±2μL/min) and temperature control stability (±0.1℃). For example, Maxi Scientific’s products comply with ISO9001:2015 quality management system certification, ensuring that the product quality meets international standards.
Liquid Chromatography Applications
In the field of biopharmaceuticals, liquid chromatography is used for protein purification and drug quality control. For example, it can separate and detect amino acids and peptides in biological samples. In food safety testing, it can analyze food additives such as preservatives and contaminants such as pesticide residues, with a detection limit as low as trace levels. In environmental monitoring, it is used to detect organic pollutants such as polycyclic aromatic hydrocarbons and phenols in water and soil.
Maxi Scientific’s products have been applied in many fields. In the food analysis project, its Ghost-Sniper Column successfully completed the separation and detection of multiple food additives, with a recovery rate of more than 95% and stable data. In the environmental testing project, the 316L stainless steel capillary matched with the liquid chromatography system realized the continuous monitoring of water samples for 240 hours, ensuring the accuracy of test results.
Conclusion
Liquid chromatography has multiple types such as HPLC, UHPLC, and 2D-LC, each with unique advantages and applicable scenarios. Maxi Scientific’s liquid chromatography-related products, with high performance, affordability, and reliable quality, can meet the needs of different industries. Whether you are engaged in biopharmaceutical research, food safety testing, or environmental monitoring, choosing Maxi Scientific’s products can help you improve analysis efficiency and reduce costs. Now, please contact Maxi Scientific immediately (call +86 400-6767580) to obtain product quotes and professional pre-sales consultation services!
Post time: Nov-26-2025